The toxicity of lead (Pb) in water is known to affect cellular components, enzymatic machinery and genomic instability. The detection of lead in water is of great significance. In this study, a method called resonant surface-enhanced LIBS (R-SENLIBS) was proposed to improve the LoD of lead in aqueous solutions. RLIBS was coupled with SENLIBS in […]
Deep-ultraviolet laser ablation with a pulsed 193 nm ArF excimer laser was used to remove localized regions from tissue sections from which proteins were extracted for spatially resolved proteomic analysis by liquid chromatography tandem mass spectrometry (LC-MS/MS). The ability to capture intact proteins by ablation at 193 nm wavelength was verified by matrix-assisted laser desorption ionization (MALDI) of the protein standard bovine serum albumin (BSA), which showed […]
Measuring neuroactivity underlying complex behaviors facilitates understanding the microcircuitry that supports these behaviors. We have developed a functional and molecular photoacoustic tomography (F/M-PAT) system which allows direct imaging of Fos-expressing neuronal ensembles in Fos-LacZ transgenic rats with a large field-of-view and high spatial resolution. F/M-PAT measures the beta-galactosidase catalyzed enzymatic product of exogenous chromophore X-gal […]
In recent years, cardiovascular disease, as the most fatal disease, has attracted widespread attention. We designed a scanning robot to detect carotid artery based on photoacoustic theory. We simply clamp the photoacoustic probe already in the laboratory on this robot. It can replace the doctor’s manual inspection. Play the role of liberating hands. In this […]
Synchronous fluorescence spectroscopy is a variation of the fluorescence technique for detection and characterization of many single ring aromatic organic molecules, polycyclic aromatic hydrocarbons, and fluorescent amino acids among other molecules. To our knowledge this technique has not been used in space exploration. In order to demonstrate the utility of this technique for planetary and astrochemical applications, we […]
Triplet photosensitizers (PSs) have attracted widespread interest due to their application in photocatalytic organic reactions, photodynamic therapy (PDT), photoinduced hydrogen production from water splitting, and triplet–triplet annihilation (TTA) upconversion. Herein, the triad T-P-Co and tetrad T-C60-P-Co were synthesized, characterized, and applied in triplet–triplet annihilation (TTA) upconversion. The photophysical processes were investigated with steady-state UV–visible absorption and fluorescence spectroscopies, nanosecond time-resolved transient absorption spectroscopy and electrochemical […]
Collagen is an important biomarker of osteoporosis progression. Noninvasive, multispectral, photoacoustic (PA) techniques use pulsed laser light to induce PA signals to facilitate the visualization of chemical components that are strongly related to tissue health. In this study, the feasibility of multi-wavelength PA (MWPA) measurement of the collagen in bone, using the wavelength range of 1300–1800 nm, was investigated. First, the feasibility […]
We report on the crystal growth, spectroscopic properties and laser performance of Tm3+-doped Bi4Si3O12 (BSO) crystal. The crystal was grown by the vertical Bridgeman method. The spectroscopic properties are investigated based on absorption and luminescence spectroscopy. Judd – Ofelt (JO) analysis is performed to calculate the spontaneous emission probabilities, branching ratio and the radiative lifetimes. The […]
This paper presents a dual-frequency piezoelectric micromachined ultrasonic transducer (pMUT) array based on thin ceramic PZT for endoscopic photoacoustic imaging (PAI) applications. With a chip size of 7×7 mm 2 , the pMUT array consists of 256 elements, half of which have a lower resonant frequency of 1.2 MHz and the other half have a higher resonant frequency of […]
New hetarylazo dyes with dihydroquinoline and tetrazole moieties with different substituents at the tetrazole cycle were synthesized and their spectral properties and thermal Z‒E isomerization were investigated in toluene, MeCN and DMSO. The substitution of H with the CH3 group at the tetrazole fragment results in the disappearance of concentration dependence of the absorption spectra observed for the dyes with unsubstituted […]