Entries by Katy

Research News- Dr. Elton Sores de Lima Filho NRC

Dr. Elton Sores de Lima Filho is currently a Research Officer with the Energy, Mining and Environment Research Centre (EME) at the National Research Council of Canada (NRC). His work focus is developing optical instruments for the measurement of materials properties. Dr. Soares de Lima Filho received his Ph.D. in Engineering Physics at Polytechnique Montreal and did his post-doctoral work at the […]

Microwave-Assisted Synthesis of Non-Fullerene Acceptors and Their Photovoltaic Studies for High-Performance Organic Solar Cells

This study explores the microwave-assisted cross-coupling methodology to synthesize non-fullerene electron acceptors for solution-processed organic solar cells. Herein, two molecules were designed by introducing the benzo [2,1,3] thiadiazole (BT) unit with a fused aromatic ring leading to an A–A′–D–A′–A (acceptor–acceptor′–donor–acceptor′–acceptor) architecture. The introduction of BT unit stabilizes the resonance structure and enhances the intramolecular charge […]

Optically Activatable Double-Drug-Loaded Perfluorocarbon Nanodroplets for On-Demand Image-Guided Drug Delivery

Phase-changing nanodroplets have been studied as externally activatable in situ microbubble precursors. The nanodroplets can be triggered to vaporize with an external optical or acoustic energy source, and the resulting microbubbles can be visualized with high sensitivity using ultrasound imaging. Because of their nanoscale size, this type of construct is attractive for the encapsulation and […]

Bodipy-Containing Porous Microcapsules for Flow Heterogeneous Photocatalysis

Photocatalysis is a facile strategy for complex chemical transformations. Heterogeneous photocatalysis, especially in the flow system, has attracted much attention as it avoids the separation of catalysts. Herein, a kind of a Bodipy-containing porous microcapsule heterogeneous photocatalyst was rationally constructed with modulation on a multiscale. The diiodo-Bodipy with methacrylate (MA-2IBDP) was synthesized as a polymerizable […]

Passivation of Electron Trap States in InP Quantum Dots with Benzoic Acid Ligands

Low toxicity indium phosphide (InP) quantum dots represent an attractive alternative to heavy-metal-based quantum dots (QDs) in numerous applications including lighting, displays, and photosensitization. However, low photoluminescence quantum yields (PLQYs) resulting from a high density of surface trap states ultimately limit the applications of as-synthesized InP QDs in commercial products. Postsynthetic treatment with Z-type ligands […]

Ambient Single-Cell Analysis and Native Tissue Imaging Using Laser-Ablation Electrospray Ionization Mass Spectrometry with Increased Spatial Resolution

Laser-ablation electrospray ionization mass spectrometry (LAESI-MS) is an emerging method that has the potential to transform the field of metabolomics. This is in part due to LAESI-MS being an ambient ionization method that requires minimal sample preparation and uses (endogenous) water for in situ analysis. This application note details the employment of the “LAESI microscope” source to […]

A Multi-Frequency pMUT Array Based on Ceramic PZT for Endoscopic Photoacoustic Imaging

This paper presents, for the first time, a multifrequency piezoelectric micromachined ultrasonic transducer (pMUT) array for endoscopic photoacoustic imaging applications. With a chip size of 3.5 × 3.5 mm 2 , the pMUT array consists of 285 pMUT elements with seven different resonant frequencies ranging from 1 MHz to 8 MHz. The pMUT array has been fabricated […]

Acoustic-resolution photoacoustic microscope based on compact and low-cost delta configuration actuator

The state-of-the-art configurations for acoustic-resolution photoacoustic (PA) microscope (AR-PAM) are large in size and expensive, hindering their democratization. While previous research on AR-PAMs introduced a low-cost light source to reduce the cost, few studies have investigated the possibility of optimizing the sensor actuation, particularly for the AR-PAM. Additionally, there is an unmet need to evaluate […]

Modeling combined ultrasound and photoacoustic imaging: Simulations aiding device development and artificial intelligence

Combined ultrasound and photoacoustic (USPA) imaging has attracted several pre-clinical and clinical applications due to its ability to simultaneously display structural, functional, and molecular information of deep biological tissue in real time. However, the depth and wavelength dependent optical attenuation and the unknown optical and acoustic heterogeneities limit the USPA imaging performance in deep tissue […]

Anomalous upconversion amplification induced by surface reconstruction in lanthanide sublattices

Upconversion nanocrystals have been extensively investigated for optical imaging and biomedical applications1,2. However, their photoluminescence is strongly attenuated by surface quenching as the nanocrystal size diminishes3. Despite considerable efforts4,5, the quenching mechanism remains poorly understood. Here we report that surface coordination of bidentate picolinic acid molecules to NaGdF4:Yb/Tm nanoparticles enhances four-photon upconversion by 11,000-fold. Mechanistic […]