Entries by Katy

Mutual impact of clinically translatable near-infrared dyes on photoacoustic image contrast and in vitro photodynamic therapy efficacy

Photodynamic therapy (PDT), a spatially localized phototoxic therapy that involves irradiation of a photosensitizer (PS) with specific wavelengths of light, has shown exceptional promise in impacting cancer treatment outcomes, particularly oral cancer. To reduce PDT outcome variability, attempts toward image-guided personalized PDT are being pursued by monitoring PS uptake either via fluorescence or photoacoustic imaging […]

Towards clinical photoacoustic and ultrasound imaging: Probe improvement and real-time graphical user interface

Photoacoustic imaging is a non-invasive and non-ionizing biomedical technique that has been investigated widely for various clinical applications. By taking the advantages of conventional ultrasound imaging, hand-held operation with a linear array transducer should be favorable for successful clinical translation of photoacoustic imaging. In this paper, we present new key updates contributed to the previously […]

Electron spin resonance resolves intermediate triplet states in delayed fluorescence

Molecular organic fluorophores are currently used in organic light-emitting diodes, though nonemissive triplet excitons generated in devices incorporating conventional fluorophores limit the efficiency. This limit can be overcome in materials that have intramolecular charge-transfer excitonic states and associated small singlet-triplet energy; triplets can then be converted to emissive singlet excitons resulting in efficient delayed fluorescence. […]

Integrated path DIAL for standoff detection of acetone vapors under topographic target condition

A mid infrared tunable Differential Absorption Lidar (DIAL) operating in the spectral region of 3000–3450 nm has been developed and its performance has been evaluated by measuring the vapors of diesel and acetone. Diesel, one of the hydrocarbon products has been used for calibration of the DIAL wavelengths. Transmittance spectrum of diesel has been measured in […]

Next Generation Cuprous Phenanthroline MLCT Photosensitizer Featuring Cyclohexyl Substituents

A new long-lived, visible-light-absorbing homoleptic Cu(I) metal-to-ligand charge transfer (MLCT) photosensitizer, [Cu(dchtmp)2]PF6 (dchtmp = 2,9-dicyclohexyl-3,4,7,8-tetramethyl-1,10-phenanthroline), has been synthesized, structurally characterized, and evaluated in terms of its molecular photophysics, electrochemistry, and electronic structure. Static and time-resolved transient absorption (TA) and photoluminescence (PL) spectroscopy measured on the title compound in CH2Cl2 (τ = 2.6 μs, ΦPL = 5.5%), CH3CN (τ […]

Fabrication of Perovskite Film-Coated Hollow Capillary Fibers Using a Fast Solvent Exchange Method

Metal halide perovskites have been successfully applied in a variety of fields such as LEDs, lasers and solar cells, thanks to their excellent optoelectronic properties. Capillary fibers can further expand the range of perovskite applications and at the same time improve its stability by encapsulating the perovskite inside the capillary. However, the high-quality perovskite film-coated […]

Thermal, optical and structural properties of relatively depolymerized sodium calcium silicate glass and glass-ceramic containing CaF2

This paper reports on the synthesis and characterization of original sodium calcium silicate glass, with CaF2 as a nucleating agent, along with the successful transformation of the as-made matrix into glass-ceramic. Characteristic temperatures of thermal events were investigated by Differential Thermal Analysis. Volumetric density, refractive index, molar volume, and electronic polarizability of the newly developed glasses […]

FTIR spectroscopic evidence for new isomers of 3-aminopyrazine-2-carboxylic acid formed in argon matrices upon UV irradiations

The UV-induced photochemistry and molecular structure of 3-aminopyrazine-2-carboxylic acid were studied in argon matrices by Fourier-transform infrared spectroscopy and B3LYP/6-311++G(2d,2p) calculations. Out of seventeen possible isomers of this molecule located on the singlet potential energy surface the most stable one, APA1 comprising intramolecular O–H···N and N–H···O hydrogen bonds, was detected experimentally in the matrix after […]

Laser Photodissociation Action Spectroscopy for the Wavelength-Dependent Evaluation of Photoligation Reactions

The nitrile imine-mediated tetrazole–ene cycloaddition is a widely used class of photoligation. Optimizing the reaction outcome requires detailed knowledge of the tetrazole photoactivation profile, which can only partially be ascertained from absorption spectroscopy, or otherwise involves laborious reaction monitoring in solution. Photodissociation action spectroscopy (PDAS) combines the advantages of optical spectroscopy and mass spectrometry in […]

Torsion-Induced Nonradiative Relaxation of the Singlet Excited State of meso-Thienyl Bodipy and Charge Separation, Charge Recombination-Induced Intersystem Crossing in Its Compact Electron Donor/Acceptor Dyads

We prepared a series of meso-thienyl boron-dipyrromethene (Bodipy) derivatives to investigate the spin–orbit charge transfer intersystem crossing (SOCT-ISC). The photophysical properties of the compounds were studied by steady-state and femtosecond/nanosecond transient absorption spectroscopy, as well as density functional theory (DFT) computations. Different from the meso-phenyl Bodipy analogues, the meso-thienyl Bodipy are weakly fluorescent. Based on femtosecond transient absorption […]